Core histone associations in solutions of high salt. An osmotic pressure study.

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Core histone associations in solutions of high salt. An osmotic pressure study.

We have measured the concentration dependence of the osmotic pressure for solutions of core histones in 2.0 M NaC1, pH 8.0, over the concentration range from 1 to 20 mg/ml at 25°C. The ratio of the osmotic pressure to the protein concentration is nearly constant over this range, with a value corresponding to an apparent number average molecular weight of 75,000. Gel filtration of a typical core...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1980

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(19)85750-2